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Is ALWAYS determined by the number of nuclides, massive nuclear particles (protons or neutrons). Of course, the number of protons ( #=Z#) determines atomic identity. Thus, I know for certain that this isotope has #15# fundamental, positively charged massive particles in its nucleus. Because it is a phosphorus atom, for which #Z# (the atomic number) #=# #15#. To account for the given atomic mass, there must be 21 neutrons in the nucleus. Handbook of banking information n toor pdf writer. This is possibly a very short-lived isotope. Nucular chemistry and physics are not my strong suites.
Is ALWAYS determined by the number of nuclides, massive nuclear particles (protons or neutrons). Of course, the number of protons ( #=Z#) determines atomic identity. Thus, I know for certain that this isotope has #15# fundamental, positively charged massive particles in its nucleus. Because it is a phosphorus atom, for which #Z# (the atomic number) #=# #15#.
To account for the given atomic mass, there must be 21 neutrons in the nucleus. This is possibly a very short-lived isotope. Nucular chemistry and physics are not my strong suites.
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The legacy of apartheid’s atomic bombs: it’s a race against time in the nuclear medicine business Every night, international flights out of Johannesburg’s OR Tambo airport carry about half a dozen anonymous-looking metal canisters the size and shape of small milk churns. But these are no ordinary containers. For one thing, they’re heavy. More importantly, they’re marked with the distinctive Danger: Radioactive logo. That’s because they hold radioactive isotopes that are on their way to medical technologists around the world. Here’s the thing: by the time the aircraft touch down, a big slice of the volatile cargo has already died off. That’s the nature of highly radioactive material, some of it with a half-life of just hours.
In fact, the deterioration starts the moment the raw material is produced. And the clock keeps ticking relentlessly.
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“The big thing with this isotope game,” says NTP Radioisotopes (Pty) Ltd boss Don Robertson, “is that there is no bloody shelf life.” From bombs to medicine Robertson heads an organisation that’s quietly established itself as a major player in the highly competitive isotope business: NTP, a division of the South Africa’s nuclear custodians, the Nuclear Energy Corporation of SA. NTP’s job is to supply raw materials worldwide for everything from silicon chip doping to molecular imaging. And it all began within a massive organisation, secluded in the valleys of Pelindaba about 30 km west of Pretoria, that was focused on “national strategic objectives” that included, among a host of other nuclear technology-related activities, the making of highly enriched uranium (90 per cent U-235) for nuclear bombs. Today the SAFARI-1 nuclear reactor uses fuel that was produced as part of the nuclear weapons programme. And the critically important medical isotopes that NTP makes and distributes worldwide are made by first bombarding plates of highly enriched uranium with intense beams of neutrons in the reactor.
Several scientists working on the bomb and other “strategic” programs (such as uranium enrichment for commercial nuclear reactors – about 4,5 per cent U-235 – and nuclear fuel assembly production for Koeberg nuclear power station) are now those running the large and growing radioisotope business at Pelindaba. Nuclear physicist Robertson himself was one of those who faced a jobless future when the weapons programme was canned in the early 1990s. “Historically, this place had about 8 000 people working here.
One of the options would have been to close it down,” he says. Last year, thanks to the increasingly successful and lucrative production of isotopes for NTP, SAFARI-1 was the world’s most effectively used reactor. Of the 15 million nuclear medicine procedures performed worldwide annually, about one-fifth use radiopharmaceuticals produced from NTP radiochemicals.
Over 150 000 of these are done locally. “Our business is export-oriented. Easily 95 per cent is in forex,” says Robertson. The company is riding the crest of a wave. “Nuclear is the flavour of the month – the energy as well as new science.” In fact, its biggest trading partner is also its biggest competitor: MDS Nordion of Canada. NTP is a big player in yttrium- 90, which it supplies to MDS for use in radioimmunotherapy, a promising new area of cancer treatment. This involves specially engineered “cancer-seeking” antibodies carrying radiation payloads to destroy malignant cells.
Because of their products’ volatility, the big 4 international suppliers of Moly-99 provide mutual backup to ensure a steady supply. “There will be times when you can’t produce,” says Robertson. “The patient has to have the product.
You are obliged to have a network.” If there’s a problem, it’s bad enough for the likes of NTP that radiation gets a bad name. “What’s worse is that the patient suffers.” Cooking up an isotope Of course, getting the product to market is only one aspect of the operation. Manufacturing is a finicky business. Well, you try picking up tiny scraps of material on the other side of a lead-brick wall a metre and a half thick, looking through lead glass nearly a metre thick. Irradiated material is manipulated and processed in a row of shielded “hot cells”, to extract the desired quantities and types of radioisotopes. In effect, these are miniature chemical factories more or less capable of creating the entire periodic table. Once purified, the resulting material, mostly molybdenum-99 (see “Isotopes and what they do” on page 6), is sent on its way in tablet, liquid or powder form.
At its destination, a medical technologist processes the radioisotope in a “generator” – basically a vial of the isotope in a shielded enclosure. To create a specific concentration of isotopes, a certain amount of chemical solution is passed through the generator and mixes with any “daughter” isotope (technetium-99) present. The resulting isotope-containing fluid is ready for use. In case you were wondering, no, there haven’t been any unpleasant incidents in transit. And even if there were, the precautions include several centimetres of shielding containing depleted uranium (nearly twice as dense as, and no more toxic than, lead).
The canister itself is NTP’s own design, subject to rigorous nuclear industry and air transport testing. Among other things, the container needs to remain intact when dropped from 9 metres on to a spike.
In the world of specialised radiation-based products for healthcare and industrial markets NTP says it is now counted amongst the top companies of its kind. It serves customers in more than 50 countries on five continents. Medical technology is not the only field to benefits from NTP’s expertise, either. For instance, the tritium generated at Pelindaba is used in luminous equipment for everything from signage to gun sights. Their product portfolio consists of five mai Isotopes and what they do An imbalance in the number of neutrons versus protons in an atom’s nucleus results in an isotope.
In Nature these are stable – an element can have various isotopes – but unstable isotopes can be produced artif.
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